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Pharmaceutical Substances

Kontakt/Bestellung
Contact/Order:

Contact/Order: info@digento.de

Hrsg. v. Jürgen Engel, Axel Kleemann, Martin Bossart, Bernhard Kutscher und Dietmar Reichert

Online

Inhalt :: Content

Referenzwerk mit Informationen zu rund 2.500 aktiven pharmazeutischen Inhaltsstoffen (APIs), die für die chemische und pharmazeutische Industrie von Interesse sind. Die Darstellungen aller Verbindungen beinhalten u.a. die chemische Struktur, die ATC-Codes, toxikologische Daten, Referenzen aus der neueren Literatur und gewerbliche Daten. Die elektronische Version bietet unter anderem die Möglichkeit, nach den in Synthesewegen enthaltenen Strukturen graphisch zu suchen.

Pharmaceutical Substances

Verlag :: Publisher

Georg Thieme Verlag

Preis :: Price

Preise auf Anfrage / Prices on request

Das Angebot richtet sich nicht an Verbraucher i. S. d. § 13 BGB und Letztverbraucher i. S. d. PAngV.

Bestellnummer bei digento :: digento order number

103459

Verlagsinformation :: Publisher's information

Pharmaceutical Substances is an online tool that presents the chemical structure and detailed synthetic route, including starting materials and intermediates, to all significant APIs. All information is extracted from patent literature compiled by experienced experts. Pharmaceutical Substances is an important knowledge base for teaching, but also for researchers and process chemists in medicinal and pharmaceutical chemistry.

Advantages of Pharmaceutical Substances (PS)

Pharmaceutical Substances is a structure-searchable resource, which is compiled by medicinal chemists with many years of experience in the pharmaceutical industry.

Pharmaceutical Substances is the Most Authorative Source for:

  • Researchers and process chemists
  • Teaching in the field of medicinal and pharmaceutical chemistry
  • Everyone involved in design, discovery, development, evaluation, and marketing of drugs


Essential Source of Information for Drug Research

  • Full synthetic route for the industrial manufacture of each drug elucidated from the patent literature
  • Unique source of reactions used on an industrial scale
  • Overview of the pharmaceutical industry from a synthetic chemist’s perspective
  • Insights into a therapeutic area and chemically related substances


Market Information for Business Development

  • Source of markets for synthesis intermediates, ingredients and enzymes
  • Patent information
  • Comprehensive coverage of older APIs and substances approved worldwide


Important Knowledge Base for Teaching

  • Capability to search for marketed drugs relating to a structure or reaction
  • A rapid overview of a therapeutic area or chemically related substances
  • Industrial synthetic routes discerned from complex patent descriptions
  • Insights into industrial processes
  • Commercial information such as trade names and vendors/manufacturers for six world markets
  • Concise records ideal for hand-outs and quick reference


Content of Pharmaceutical Substances (PS)

Pharmaceutical Substances presents the chemical structure and synthetic route, including intermediates, to all significant APIs. It covers detailed information about each drug.

Factual data

  • International Nonproprietary Names (INN)
  • Trivial names and synonyms
  • Chemical name (IUPAC chemical substance naming convention)
  • Anatomical Therapeutic Chemical (ATC) Codes
  • CAS numbers
  • Molecular formula and weight
  • Major uses and medical applications
  • Patent number, origin, holder and date of application
  • Commercial information


Intermediates

  • Key intermediates in the synthetic pathways are listed by name, molecular formula and CAS number to allow efficient searching for sources of supply.
  • Synthetic route(s) used for industrial large-scale production
  • Great care is taken by the authors to ascertain the synthetic route(s) used for industrial large-scale production of the drugs listed. A detailed description of the preparation of each substance is provided, including the synthesis of intermediates. In many cases, different synthetic routes are described, especially for the most economically important drugs.


Trade names and vendors

For the six most important markets, trade names and the names of companies that produce and market the product are given. Years of introduction are added in those cases where they differ from the date the original patent was granted. If a product has been withdrawn from the market, this information is also included.


Formulations

The most important pharmaceutical dosage forms are provided to enable the user to assess the order of magnitude a compound is needed in, thus helping to estimate its commercial value.


Substance classes

The key structural units in each API are identified and links are provided to other APIs containing this unit.


Enzyme classes

If enzymes, microorganisms, or plant or animal tissues are involved in a synthesis, they are also listed and are linked to other syntheses in which they are involved.

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